Recombinant Mouse IL21 / Interleukin 21 Protein

$ 108.00 – $ 3,578.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP10462
Species: Mouse
Available Tags: Untagged
Host: E. coli
Purity: Greater than 98% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 129

Product Number	Description	Price
QP10462-ec-2ug	Size: 2 ug, Tag: Untagged (Native Protein)	$ 98.00
QP10462-ec-10ug	Size: 10 ug, Tag: Untagged (Native Protein)	$ 248.00
QP10462-ec-100ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 1,778.00
QP10462-ec-250ug	Size: 250 ug, Tag: Untagged (Native Protein)	$ 3,188.00

Shipping Information

7-10 days

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP10462-ec-2ug

Recombinant Mouse IL21 / Interleukin 21 Protein General Information
Alternate Names
IL21; Interleukin 21; IL-21
Curated Database and Bioinformatic Data
Gene Symbol	IL21
Entrez Gene ID	60505
Ensemble Gene ID	ENSMUSG00000027718
RefSeq Protein Accession(s)	NP_068554.1
RefSeq mRNA Accession(s)	NM_021782.3
UniProt ID(s)	Q9ES17
UniGene ID(s)	Mm.157689
COSMIC ID Link(s)	IL21
KEGG Gene ID(s)	mmu:60505
General Description of Recombinant Mouse IL21 / Interleukin 21 Protein.
Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (By similarity). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.

Mouse IL21 / Interleukin 21 Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant IL21 / Interleukin 21 based upon sequence from: Mouse

Host: QP10462 protein expressed in E. coli.

Tag: Untagged

Protein Construction: A DNA sequence encoding the Mouse IL21 / Interleukin 21, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP10462.

Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using human N1186 T cells is less than 25 ng/ml, corresponding to a specific activity of > 4.0 Ã 104 IU/mg.

Full Length? Partial (see sequence information for more details).

Amino Acid Sequence: HKSSPQGPDR LLIRLRHLID IVEQLKIYEN DLDPELLSAP QDVKGHCEHA AFACFQKAKL KPSNPGNNKT FIIDLVAQLR RRLPARRGGK KQKHIAKCPS CDSYEKRTPK EFLERLKWLL QKMIHQHLS

Purity: Greater than 98% as determined by SDS-PAGE and HPLC.

Reconstitution Instructions:

Concentration of Mouse IL21 / Interleukin 21 Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.

Buffer: 0.2 m filtered 2 Ã PBS, pH 7.4, lyophilized

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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