PDF DatasheetHuman Parathyroid Hormone Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Parathyroid Hormone based upon sequence from: Human
Host: QP10148 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human Parathyroid Hormone, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10148.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by its ability to induce cAMP accumulation in murine MC3T3E1 cells is less than 50 ng/ml, corresponding to a specific activity of > 2.0 × 104 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: SVSEIQLMHN LGKHLNSMER VEWLRKKLQD VHNF
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human Parathyroid Hormone Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Parathyroid Hormone Protein General Information | |
|---|---|
| Alternate Names | |
| Parathyroid Hormone; PTH1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PTH |
| Entrez Gene ID | 5741 |
| Ensemble Gene ID | ENSG00000152266 |
| RefSeq Protein Accession(s) | NP_000306.1 |
| RefSeq mRNA Accession(s) | NM_000315.3 |
| UniProt ID(s) | P01270 |
| UniGene ID(s) | Hs.37045 |
| HGNC ID(s) | HGNC:9606 |
| COSMIC ID Link(s) | PTH |
| KEGG Gene ID(s) | hsa:5741 |
| PharmGKB ID(s) | PA33951 |
| General Description of Recombinant Human Parathyroid Hormone Protein. | |
| PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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