PDF DatasheetHuman CCL13 / MCP-4 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL13 / MCP-4 based upon sequence from: Human
Host: QP10233 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human CCL13 / MCP-4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10233.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration of 10-100 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: QPDALNVPST CCFTFSSKKI SLQRLKSYVI TTSRCPQKAV IFRTKLGKEI CADPKEKWVQ NYMKHLGRKA HTLKT
Purity: Greater than 96% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human CCL13 / MCP-4 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CCL13 / MCP-4 Protein General Information | |
|---|---|
| Alternate Names | |
| CCL13; MCP-4; NCC1; SCYL1; NCC-1; SCYA13; CKb10; MCP-4 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL13 |
| Entrez Gene ID | 6357 |
| Ensemble Gene ID | ENSG00000181374 |
| RefSeq Protein Accession(s) | NP_005399.1 |
| RefSeq mRNA Accession(s) | NM_005408.2 |
| UniProt ID(s) | Q99616 |
| UniGene ID(s) | Hs.414629 |
| HGNC ID(s) | HGNC:10611 |
| COSMIC ID Link(s) | CCL13 |
| KEGG Gene ID(s) | hsa:6357 |
| PharmGKB ID(s) | PA35544 |
| General Description of Recombinant Human CCL13 / MCP-4 Protein. | |
| Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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