PDF DatasheetHuman CCL20 / MIP-3 alpha Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL20 / MIP-3 alpha based upon sequence from: Human
Host: QP5271 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5271.
Bioactivity Data: Human CCL20 / MIP-3 alpha induces Primary human T cell chemotaxis.
Monomer or Dimer: Monomer
Amino Acid Sequence: ASNFDCCLGY TDRILHPKFI VGFTRQLANE GCDINAIIFH TKKKLSVCAN PKQTWVKYIV RLLSKKVKNM
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human CCL20 / MIP-3 alpha Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human CCL20 / MIP-3 alpha Protein General Information | |
|---|---|
| Alternate Names | |
| CCL20, MIP-3 alpha, MIP-3-alpha, MIP-3a, SCYA20, CKb4, MIP3A, ST38, LARC, Exodus | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL20 |
| Entrez Gene ID | 6364 |
| Ensemble Gene ID | ENSG00000115009 |
| RefSeq Protein Accession(s) | NP_001123518.1 |
| RefSeq mRNA Accession(s) | NM_001130046.1, NM_004591.2 |
| UniProt ID(s) | P78556 |
| UniGene ID(s) | Hs.75498 |
| HGNC ID(s) | HGNC:10619 |
| COSMIC ID Link(s) | CCL20 |
| KEGG Gene ID(s) | hsa:6364 |
| PharmGKB ID(s) | PA35551 |
| General Description of Recombinant Human CCL20 / MIP-3 alpha Protein . | |
| Macrophage inflammatory protein-3 alpha (MIP-3-alpha), also called CCL20, is expressed in the liver, lungs, lymph nodes, and peripheral blood lymphocytes. MIP-3-alpha expression is strongly induced by inflammatory signals, and downregulated by the anti-inflammatory cytokine interleukin-10 (IL-10). MIP-3-alpha signals through the G protein-coupled receptor CCR6 to function as a chemoattractant to lymphocytes and dendritic cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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