PDF DatasheetMouse CCL20 / MIP-3 alpha Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL20 / MIP-3 alpha based upon sequence from Mouse
Host: QP1448 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP1448.
Bioactivity Data: Mouse CCL20 / MIP-3 alpha induces Primary human T cell chemotaxis (significanty different from control at Mouse CCL20 / MIP-3 alpha concentrations greater than 5 ng/ml)
Monomer or Dimer: Monomer
Amino Acid Sequence: ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Mouse CCL20 / MIP-3 alpha Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Mouse CCL20 / MIP-3 alpha Protein General Information | |
|---|---|
| Alternate Names | |
| CCL20, MIP-3 alpha, MIP-3-alpha, MIP-3a, SCYA20, CKb4, MIP3A, ST38, LARC, Exodus | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL20 |
| Entrez Gene ID | 20297 |
| Ensemble Gene ID | ENSMUSG00000026166 |
| RefSeq Protein Accession(s) | NP_001153210.1 |
| RefSeq mRNA Accession(s) | NM_001159738.1, NM_016960.2 |
| UniProt ID(s) | O89093 |
| UniGene ID(s) | Mm.116739 |
| COSMIC ID Link(s) | CCL20 |
| KEGG Gene ID(s) | mmu:20297 |
| General Description of Recombinant Mouse CCL20 / MIP-3 alpha Protein . | |
| Macrophage inflammatory protein-3 alpha (MIP-3-alpha), also called CCL20, is expressed in the liver, lungs, lymph nodes, and peripheral blood lymphocytes. MIP-3-alpha expression is strongly induced by inflammatory signals, and downregulated by the anti-inflammatory cytokine interleukin 10 (IL-10). MIP-3-alpha signals through the G protein-coupled receptor CCR6 to function as a chemoattractant to lymphocytes and dendritic cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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