PDF DatasheetHuman CCL20 / MIP-3 alpha Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL20 / MIP-3 alpha based upon sequence from: Human
Host: QP10235 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human CCL20 / MIP-3 alpha, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10235.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 10-50 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: ASNFDCCLGY TDRILHPKFI VGFTRQLANE GCDINAIIFH TKKKLSVCAN PKQTWVKYIV RLLSKKVKNM
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human CCL20 / MIP-3 alpha Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CCL20 / MIP-3 alpha Protein General Information | |
|---|---|
| Alternate Names | |
| CCL20; MIP-3 alpha; MIP-3-alpha; MIP-3a; SCYA20; CKb4; MIP3A; ST38; LARC; Exodus | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL20 |
| Entrez Gene ID | 6364 |
| Ensemble Gene ID | ENSG00000115009 |
| RefSeq Protein Accession(s) | NP_001123518.1 |
| RefSeq mRNA Accession(s) | NM_001130046.1, NM_004591.2 |
| UniProt ID(s) | P78556 |
| UniGene ID(s) | Hs.75498 |
| HGNC ID(s) | HGNC:10619 |
| COSMIC ID Link(s) | CCL20 |
| KEGG Gene ID(s) | hsa:6364 |
| PharmGKB ID(s) | PA35551 |
| General Description of Recombinant Human CCL20 / MIP-3 alpha Protein. | |
| Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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