PDF DatasheetHuman CXCL12 / SDF-1 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CXCL12 / SDF-1 based upon sequence from: Human
Host: QP5326 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5326.
Bioactivity Data: Human CXCL12 / SDF-1 induces Primary human T cell chemotaxis (significanty different from control at Human CXCL12 / SDF-1 concentrations greater than 5-20 ng/ml).
Monomer or Dimer: Monomer
Amino Acid Sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human CXCL12 / SDF-1 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human CXCL12 / SDF-1 Protein General Information | |
|---|---|
| Alternate Names | |
| CXCL12, SDF-1, SCYB12, IRH, PBSF, SDF1, TPAR1, TLSF | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CXCL12 |
| Entrez Gene ID | 6387 |
| Ensemble Gene ID | ENSG00000107562 |
| RefSeq Protein Accession(s) | NP_000600.1 |
| RefSeq mRNA Accession(s) | NM_000609.6, NM_001033886.2, NM_001178134.1, NM_001277990.1, NM_199168.3 |
| UniProt ID(s) | P48061 |
| UniGene ID(s) | Hs.522891 |
| HGNC ID(s) | HGNC:10672 |
| COSMIC ID Link(s) | CXCL12 |
| KEGG Gene ID(s) | hsa:6387 |
| PharmGKB ID(s) | PA35602 |
| General Description of Recombinant Human CXCL12 / SDF-1 Protein . | |
| Stromal cell-derived factor-1 alpha (SDF-1a), also called CXCL12a, is one of two SDF-1 splice variants made by a wide variety of cells upon stimulation by inflammatory cytokines such as TNF, IL-1, and LPS. SDF-1a signals through the G protein-coupled receptor CXCR4 to recruit activated leukocytes. Human and mouse SDF-1a share 99% sequence identity. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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