PDF DatasheetHuman EGF / Epidermal Growth Factor Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant EGF / Epidermal Growth Factor based upon sequence from: Human
Host: QP5335 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5335.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 100 pg/mL in the 3T3 cell proliferation assay. The bioactivity acceptance criteria is set at 1 x 10^7 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: NSDSECPLSH DGYCLHDGV C MYIEALDK YA CNCVVGY IGE RCQYRD LKWW ELR
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human EGF / Epidermal Growth Factor Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human EGF / Epidermal Growth Factor Protein (Animal Free) General Information | |
|---|---|
| Alternate Names | |
| EGF, Epidermal Growth Factor, URG, HOMG4 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | EGF |
| Entrez Gene ID | 1950 |
| Ensemble Gene ID | ENSG00000138798 |
| RefSeq Protein Accession(s) | NP_001171601.1 |
| RefSeq mRNA Accession(s) | NM_001178130.2, NM_001178131.2, NM_001963.5 |
| UniProt ID(s) | P01133 |
| UniGene ID(s) | Hs.419815 |
| HGNC ID(s) | HGNC:3229 |
| COSMIC ID Link(s) | EGF |
| KEGG Gene ID(s) | hsa:1950 |
| PharmGKB ID(s) | PA27664 |
| General Description of Recombinant Human EGF / Epidermal Growth Factor Protein (Animal Free). | |
| Epidermal growth factor (EGF) is a growth factor that stimulates the proliferation, differentiation, and survival of epithelial and epidermal cells. EGF contains three intramolecular disulfide bonds and binds in high affinity to the epidermal growth factor receptor (EGFR). EGF is overexpressed in multiple tumor cell lines and promotes resistance to chemotherapy and radiation treatments. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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