PDF DatasheetHuman GDNF Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant GDNF based upon sequence from: Human
Host: QP5221 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5221.
Bioactivity Data: C6 proliferation significantly induced by less than 3 ug/ml of Human GDNF, or activity of at least 3.3 x 10^2 units/mg.
Monomer or Dimer: Dimer
Amino Acid Sequence: MSPDKQMAVL PRRERNRQAA AANPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCDAAETTY DKILKNLSRN RRLVSDKVGQ ACCRPIAFDD DLSFLDDNLV YHILRKHSAK RCGCI
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human GDNF Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium citrate, 100 mM sodium chloride, pH 4.0
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human GDNF Protein General Information | |
|---|---|
| Alternate Names | |
| GDNF, ATF1, ATF, HSCR3, ATF2, HFB1-GDNF | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | GDNF |
| Entrez Gene ID | 2668 |
| Ensemble Gene ID | ENSG00000168621 |
| RefSeq Protein Accession(s) | NP_000505.1 |
| RefSeq mRNA Accession(s) | NM_000514.3, NM_001190468.1, NM_001190469.1, NM_001278098.1, NM_199231.2, XM_011514030.2, XM_017009337.1 |
| UniProt ID(s) | P39905 |
| UniGene ID(s) | Hs.248114 |
| HGNC ID(s) | HGNC:4232 |
| COSMIC ID Link(s) | GDNF |
| KEGG Gene ID(s) | hsa:2668 |
| PharmGKB ID(s) | PA28644 |
| General Description of Recombinant Human GDNF Protein . | |
| Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to activate receptor tyrosine kinase RET signaling. GDNF promotes dopamine uptake, prevents motor neuron apoptosis, and supports the survival and differentiation of neurons. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.