PDF DatasheetMouse GDNF Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant GDNF based upon sequence from: Mouse
Host: QP5447 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5447.
Bioactivity Data: Bioactivity of recombinant GDNF is confirmed by C6 cell proliferation assay (see figure).
Monomer or Dimer: Dimer
Amino Acid Sequence: MSPDKQAALP RRENRNRQAA AASPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCESAETMY DKILKNLSRS RRLTSDKVGQ ACCRPVAFDD DLSFLDDNLV YHILRKHSAK RCGCI
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse GDNF Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Mouse GDNF Protein (Animal Free) General Information | |
|---|---|
| Alternate Names | |
| GDNF, ATF1, ATF, HSCR3, ATF2, HFB1-GDNF | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | GDNF |
| Entrez Gene ID | 14573 |
| Ensemble Gene ID | ENSMUSG00000022144 |
| RefSeq Protein Accession(s) | NP_001288261.1 |
| RefSeq mRNA Accession(s) | NM_001301332.1, NM_001301357.1, NM_010275.3 |
| UniProt ID(s) | P48540 |
| UniGene ID(s) | Mm.4679 |
| COSMIC ID Link(s) | GDNF |
| KEGG Gene ID(s) | mmu:14573 |
| General Description of Recombinant Mouse GDNF Protein (Animal Free). | |
| Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to activate receptor tyrosine kinase RET signaling. GDNF promotes dopamine uptake, prevents motor neuron apoptosis, and supports the survival and differentiation of neurons. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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