PDF DatasheetHuman GDNF Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant GDNF based upon sequence from: Human
Host: QP10417 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human GDNF, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10417.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using rat C6 cells is less than 0.1 ng/ml, corresponding to a specific activity of > 5.0 × 107 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: SPDKQMAVLP RRERNRQAAA ANPENSRGKG RRGQRGKNRG CVLTAIHLNV TDLGLGYETK EELIFRYCSG SCDAAETTYD KILKNLSRNR RLVSDKVGQA CCRPIAFDDD LSFLDDNLVY HILRKHSAKR CGCI
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human GDNF Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 m filtered 1 × PBS, pH 7.4, with 0.05 % Tween-20, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human GDNF Protein General Information | |
|---|---|
| Alternate Names | |
| GDNF; ATF1; ATF; HSCR3; ATF2; HFB1-GDNF | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | GDNF |
| Entrez Gene ID | 2668 |
| Ensemble Gene ID | ENSG00000168621 |
| RefSeq Protein Accession(s) | NP_000505.1 |
| RefSeq mRNA Accession(s) | NM_000514.3, NM_001190468.1, NM_001190469.1, NM_001278098.1, NM_199231.2, XM_011514030.2, XM_017009337.1 |
| UniProt ID(s) | P39905 |
| UniGene ID(s) | Hs.248114 |
| HGNC ID(s) | HGNC:4232 |
| COSMIC ID Link(s) | GDNF |
| KEGG Gene ID(s) | hsa:2668 |
| PharmGKB ID(s) | PA28644 |
| General Description of Recombinant Human GDNF Protein. | |
| Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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