PDF DatasheetHuman I-TAC / CXCL11 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant I-TAC / CXCL11 based upon sequence from Human
Host: QP1189 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Immunogen, Protein Standard, Other Cell Biology Applications
Application Notes: Please contact us for application specific information for QP1189.
Bioactivity Data: Untested
Monomer or Dimer: Monomer
Amino Acid Sequence: FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Human I-TAC / CXCL11 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human I-TAC / CXCL11 Protein General Information | |
|---|---|
| Alternate Names | |
| I-TAC, CXCL11, I-TAC, IP-9, SCYB11, IP9, SCYB9B, H174, b-R1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CXCL11 |
| Entrez Gene ID | 6373 |
| Ensemble Gene ID | ENSG00000169248 |
| RefSeq Protein Accession(s) | NP_001289052.1 |
| RefSeq mRNA Accession(s) | NM_001302123.1, NM_005409.4 |
| UniProt ID(s) | O14625 |
| UniGene ID(s) | Hs.632592 |
| HGNC ID(s) | HGNC:10638 |
| COSMIC ID Link(s) | CXCL11 |
| KEGG Gene ID(s) | hsa:6373 |
| PharmGKB ID(s) | PA35569 |
| General Description of Recombinant Human I-TAC / CXCL11 Protein . | |
| Interferon-inducible T cell alpha chemoattractant (I-TAC), or CXCL11, is expressed at high levels in leukocytes, pancreas, and liver cells. I-TAC gene expression is induced by interferons alpha (IFN-a), beta (IFN-b), and gamma (IFN-g). I-TAC is the dominant ligand known to bind the chemokine receptor CXCR3, thus acting as a stronge agonist. I-TAC functions as a chemoattractant for interleukin 2 (IL-2)-activated T cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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