PDF DatasheetMouse I-TAC / CXCL11 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant I-TAC / CXCL11 based upon sequence from: Mouse
Host: QP10257 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Mouse I-TAC / CXCL11, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10257.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using murine CXCR3 transfected 293 cells is in a concentration of 10-100 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: FLMFKQGRCL CIGPGMKAVK MAEIEKASVI YPSNGCDKVE VIVTMKAHKR QRCLDPRSKQ ARLIMQAIEK KNFLRRQNM
Purity: Greater than 98% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Mouse I-TAC / CXCL11 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse I-TAC / CXCL11 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CXCL11 |
| Entrez Gene ID | 56066 |
| RefSeq Protein Accession(s) | NP_062367.1 |
| RefSeq mRNA Accession(s) | NM_019494.1 |
| UniProt ID(s) | Q9JHH5 |
| UniGene ID(s) | Mm.131723 |
| COSMIC ID Link(s) | CXCL11 |
| KEGG Gene ID(s) | mmu:56066 |
| General Description of Recombinant Mouse I-TAC / CXCL11 Protein. | |
| Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses (By similarity). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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