PDF DatasheetHuman M-CSF / CSF-1 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant M-CSF / CSF-1 based upon sequence from: Human
Host: QP5223 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5223.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 10 ng/mL in the NFS-60 cell proliferation assay. The bioactivity acceptance criteria is set at 1 x 10^5 units/mg.
Monomer or Dimer: Dimer
Amino Acid Sequence: MEEVSEYCSH MIGSGHLQSL QRLIDSQMET SCQITFEFVD QEQLKDPVCY LKKAFLLVQD IMEDTMRFRD NTPNAIAIVQ LQELSLRLKS CFTKDYEEHD KACVRTFYET PLQLLEKVKN VFNETKNLLD KDWNIFSKNC NNSFAECSSQ GHERQSEGS
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human M-CSF / CSF-1 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, 50 mM sodium chloride, pH 8.0
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human M-CSF / CSF-1 Protein General Information | |
|---|---|
| Alternate Names | |
| M-CSF, CSF-1, C87615, MCSF, Csfm | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CSF1 |
| Entrez Gene ID | 1435 |
| Ensemble Gene ID | ENSG00000184371 |
| RefSeq Protein Accession(s) | NP_000748.3 |
| RefSeq mRNA Accession(s) | NM_000757.5, NM_172210.2, NM_172211.3, NM_172212.2 |
| UniProt ID(s) | P09603 |
| UniGene ID(s) | Hs.173894 |
| HGNC ID(s) | HGNC:2432 |
| COSMIC ID Link(s) | CSF1 |
| KEGG Gene ID(s) | hsa:1435 |
| PharmGKB ID(s) | PA26935 |
| General Description of Recombinant Human M-CSF / CSF-1 Protein. | |
| Macrophage colony stimulating factor (M-CSF) is a hematopoietic growth factor that is widely produced by a variety of cells. M-CSF stimulates the proliferation and differentiation of hematopoietic stem cells into monocyte and macrophage cell types. M-CSF also acts through the colony stimulating factor 1 receptor (CSF1R) to modulate processes involved in immunology, bone metabolism, fertility, and pregnancy. Human M-CSF shows activity on mouse cells; however, mouse CSF shows no activity on human cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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