PDF DatasheetHuman MIF / GLIF Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant MIF / GLIF based upon sequence from: Human
Host: QP5276 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5276.
Bioactivity Data: Human MIF / GLIF induces IL-8 production in human PBMCs. Activity was further confirmed by measuring chemotaxisof U937 cells via agarose microdroplet assay.
Monomer or Dimer: Monomer
Amino Acid Sequence: MPMFIVNTNV PRASVPDGFL SELTQQLAQA TGKPPQYIAV HVVPDQLMAF GGSSEPCALC SLHSIGKIGG AQNRSYSKLL CGLLAERLRI SPDRVYINYY DMNAANVGWN NSTFA
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human MIF / GLIF Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human MIF / GLIF Protein General Information | |
|---|---|
| Alternate Names | |
| MIF, GLIF, MMIF, GLIF, GIF | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MIF |
| Entrez Gene ID | 4282 |
| Ensemble Gene ID | ENSG00000240972 |
| RefSeq Protein Accession(s) | NP_002406.1 |
| RefSeq mRNA Accession(s) | NM_002415.1 |
| UniProt ID(s) | P14174 |
| UniGene ID(s) | Hs.407995 |
| HGNC ID(s) | HGNC:7097 |
| COSMIC ID Link(s) | MIF |
| KEGG Gene ID(s) | hsa:4282 |
| PharmGKB ID(s) | PA30819 |
| General Description of Recombinant Human MIF / GLIF Protein . | |
| Macrophage migration inhibitory factor (MIF) is a pro-inflammatory lymphokine that functions during cell-mediated immmunity. MIF promotes fibroblast migration by inducing interleukin 1 (IL-1), interleukin 8 (IL-8), and matrix metalloproteinase (MMP) expression. In interferon-gamma-activated macrophages, MIF stimulates nitric oxide (NO) production and tumor necrosis factor-alpha (TNF-a) secretion. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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