PDF DatasheetHuman MIF / GLIF Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant MIF / GLIF based upon sequence from: Human
Host: QP8560 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) MIF / GLIF, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8560.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Pro2 – Ala115
Amino Acid Sequence: PMFIVNTNVP RASVPDGFLS ELTQQLAQAT GKPPQYIAVH VVPDQLMAFG GSSEPCALCS LHSIGKIGGA QNRSYSKLLC GLLAERLRIS PDRVYINYYD MNAANVGWNN STFA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human MIF / GLIF Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human MIF / GLIF Protein General Information | |
|---|---|
| Alternate Names | |
| MIF; GLIF; MMIF; GLIF; GIF | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MIF |
| Entrez Gene ID | 4282 |
| Ensemble Gene ID | ENSG00000240972 |
| RefSeq Protein Accession(s) | NP_002406.1 |
| RefSeq mRNA Accession(s) | NM_002415.1 |
| UniProt ID(s) | P14174 |
| UniGene ID(s) | Hs.407995 |
| HGNC ID(s) | HGNC:7097 |
| COSMIC ID Link(s) | MIF |
| KEGG Gene ID(s) | hsa:4282 |
| PharmGKB ID(s) | PA30819 |
| General Description of Recombinant Human MIF / GLIF Protein. | |
| Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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