PDF DatasheetHuman SCF / C-kit ligand Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant SCF / C-kit ligand based upon sequence from: Human
Host: QP5225 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5225.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 15 ng/mL in the TF-1 cell proliferation assay. The bioactivity acceptance criteria is set at 6.6 x 10^4 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MEGICRNRVT NNVKDVTKLV ANLPKDYMIT LKYVPGMDVL PSHCWISEMV VQLSDSLTDL LDKFSNISEG LSNYSIIDKL VNIVDDLVEC VKENSSKDLK KSFKSPEPRL FTPEEFFRIF NRSIDAFKDF VVASETSDCV VSSTLSPEKD SRVSVTKPFM LPPVA
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human SCF / C-kit ligand Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM acetic acid
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human SCF / C-kit ligand Protein General Information | |
|---|---|
| Alternate Names | |
| SCF, C-kit ligand, FPH2, DCUA, Kitl, SHEP7, SCF, DFNA69, SF, FPHH, KL-1, MGF | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | KITLG |
| Entrez Gene ID | 4254 |
| Ensemble Gene ID | ENSG00000049130 |
| RefSeq Protein Accession(s) | NP_000890.1 |
| RefSeq mRNA Accession(s) | NM_000899.4, NM_003994.5 |
| UniProt ID(s) | P21583 |
| UniGene ID(s) | Hs.1048 |
| HGNC ID(s) | HGNC:6343 |
| COSMIC ID Link(s) | KITLG |
| KEGG Gene ID(s) | hsa:4254 |
| PharmGKB ID(s) | PA30129 |
| General Description of Recombinant Human SCF / C-kit ligand Protein. | |
| Stem cell factor (SCF) is a cytokine made by fibroblasts and endothelial cells. SCF binds to the receptor c-Kit/CD117 and plays a critical role in the maintenance, survival, and differentiation of hematopoietic stem cells. Human SCF shows no activity on murine cells, but murine and rat SCF are active on human cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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