PDF DatasheetRat SCF / C-kit ligand Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant SCF / C-kit ligand based upon sequence from Rat
Host: QP5517 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5517.
Bioactivity Data: Rat SCF / C-kit ligand induces TF-1 cell proliferation (typical ED50 is ? 15 ng/ml).
Monomer or Dimer: Monomer
Amino Acid Sequence: MQEICRNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV THLSVSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVAC MEENAPKNVK ESLKKPETRN FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Rat SCF / C-kit ligand Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Rat SCF / C-kit ligand Protein General Information | |
|---|---|
| Alternate Names | |
| SCF, C-kit ligand, FPH2, DCUA, Kitl, SHEP7, SCF, DFNA69, SF, FPHH, KL-1, MGF | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | KITLG |
| Entrez Gene ID | 60427 |
| Ensemble Gene ID | ENSRNOG00000005386 |
| RefSeq Protein Accession(s) | NP_068615.1 |
| RefSeq mRNA Accession(s) | NM_021843.4 |
| UniProt ID(s) | P21581 |
| UniGene ID(s) | Rn.44216 |
| COSMIC ID Link(s) | KITLG |
| KEGG Gene ID(s) | rno:60427 |
| General Description of Recombinant Rat SCF / C-kit ligand Protein . | |
| Stem cell factor (SCF) is a cytokine made by fibroblasts and endothelial cells. SCF binds to the receptor c-Kit/CD117 and plays a critical role in the maintenance, survival, and differentiation of hematopoietic stem cells. Human SCF shows no activity on murine cells, but murine and rat SCF are active on human cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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