PDF DatasheetHuman Thrombopoietin / THPO Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Thrombopoietin / THPO based upon sequence from: Human
Host: QP5227 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5227.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 5 ng/mL in the MO7e cell proliferaiton assay. The bioactivity acceptance criteria is set at 2 x 10^5 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MSPAPPACDL RVLSKLLRDS HVLHSRLSQC PEVHPLPTPV LLPAVDFSLG EWKTQMEETK AQDILGAVTL LLEGVMAARG QLGPTCLSSL LGQLSGQVRL LLGALQSLLG TQLPPQGRTT AHKDPNAIFL SFQHLLRGKV RFLMLVGGST LCVRRAPPTT AVPSRTSLVL TLNEL
Purity: Greater than 90 as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Thrombopoietin / THPO Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human Thrombopoietin / THPO Protein (Animal Free) General Information | |
|---|---|
| Alternate Names | |
| Thrombopoietin, THPO, MPLLG, MKCSF, THCYT1, TPO, MGDF, ML | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | THPO |
| Entrez Gene ID | 7066 |
| Ensemble Gene ID | ENSG00000090534 |
| RefSeq Protein Accession(s) | NP_000451.1 |
| RefSeq mRNA Accession(s) | NM_000460.3, NM_001177597.2, NM_001177598.2, NM_001289997.1, NM_001289998.1, NM_001290003.1, NM_001290022.1, NM_001290026.1, NM_001290027.1, NM_001290028.1 |
| UniProt ID(s) | P40225 |
| UniGene ID(s) | Hs.1166 |
| HGNC ID(s) | HGNC:11795 |
| COSMIC ID Link(s) | THPO |
| KEGG Gene ID(s) | hsa:7066 |
| PharmGKB ID(s) | PA36506 |
| General Description of Recombinant Human Thrombopoietin / THPO Protein (Animal Free). | |
| Thrombopoietin (TPO) is a growth factor that is produced by liver and kidney tissues. TPO binds the TPO receptor (CD110) to promote megakaryocyte maturation, differentiation, and the production of platelets. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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