PDF DatasheetMouse Thrombopoietin / THPO Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Thrombopoietin / THPO based upon sequence from: Mouse
Host: QP10468 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Mouse Thrombopoietin / THPO, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10468.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using human MO7e cells is less than 1.0 ng/ml, corresponding to a specific activity of > 1.0 × 106 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: SPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKF
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Mouse Thrombopoietin / THPO Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, with 5% Trehalose, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse Thrombopoietin / THPO Protein General Information | |
|---|---|
| Alternate Names | |
| Thrombopoietin; THPO; MPLLG; MKCSF; THCYT1; TPO; MGDF; ML | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | THPO |
| Entrez Gene ID | 21832 |
| Ensemble Gene ID | ENSMUSG00000022847 |
| RefSeq Protein Accession(s) | NP_001166976.1 |
| RefSeq mRNA Accession(s) | NM_001173505.1, NM_001289894.1, NM_009379.3 |
| UniProt ID(s) | P40226 |
| UniGene ID(s) | Mm.3943 |
| COSMIC ID Link(s) | THPO |
| KEGG Gene ID(s) | mmu:21832 |
| General Description of Recombinant Mouse Thrombopoietin / THPO Protein. | |
| Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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