PDF DatasheetMouse IGF1 / IGF-I Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IGF1 / IGF-I based upon sequence from: Mouse
Host: QP5404 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5404.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 20 ng/mL in the FDC-P1 cell proliferation assay. The bioactivity acceptance criteria is set at 5.0 x 10^4 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: GPETLCGAEL VDALQFVCGP RGFYFNKPTG YGSSIRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPTKAA
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse IGF1 / IGF-I Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Mouse IGF1 / IGF-I Protein General Information | |
|---|---|
| Alternate Names | |
| IGF1, IGF-I, Igf-1, Igf-I, C730016P09Rik | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IGF1 |
| Entrez Gene ID | 16000 |
| Ensemble Gene ID | ENSMUSG00000020053 |
| RefSeq Protein Accession(s) | NP_001104744.1 |
| RefSeq mRNA Accession(s) | NM_001111274.1, NM_001111276.1 |
| UniProt ID(s) | Q8CAR0 |
| UniGene ID(s) | Mm.268521 |
| COSMIC ID Link(s) | IGF1 |
| General Description of Recombinant Mouse IGF1 / IGF-I Protein. | |
| Insulin-like growth factor I (IGF-I) is a growth factor that is produced by the liver. IGF-1 production is stimulated by growth hormone (GH). IGF-I binds the insulin-like growth factor 1 receptor (IGF1R) and the insulin receptor to stimulate systemic body growth. IGF-I is one of the most potent activators of the AKT signaling pathway, which stimulates cell proliferation and inhibits programmed cell death. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.