PDF DatasheetRat IGF1 / IGF-I Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IGF1 / IGF-I based upon sequence from Rat
Host: QP5492 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5492.
Bioactivity Data: Rat IGF1 / IGF-I induces MCF-7 cell proliferation (typical ED50 is ? 100 ng/ml).
Monomer or Dimer: Monomer
Amino Acid Sequence: GPETLCGAEL VDALQFVCGP RGFYFNKPTG YGSSIRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPTKSA
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Rat IGF1 / IGF-I Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Rat IGF1 / IGF-I Protein General Information | |
|---|---|
| Alternate Names | |
| IGF1, IGF-I, Igf-1, Igf-I, C730016P09Rik | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IGF1 |
| Entrez Gene ID | 24482 |
| Ensemble Gene ID | ENSRNOG00000004517 |
| RefSeq Protein Accession(s) | NP_001075946.2 |
| RefSeq mRNA Accession(s) | NM_001082477.2, NM_001082478.1, NM_001082479.1, XM_006241191.2, XM_006241192.1, XM_006241193.3 |
| UniProt ID(s) | P08025 |
| UniGene ID(s) | Rn.201887 |
| COSMIC ID Link(s) | IGF1 |
| KEGG Gene ID(s) | rno:24482 |
| General Description of Recombinant Rat IGF1 / IGF-I Protein . | |
| Insulin-like growth factor I (IGF-I) is a growth factor that is produced by the liver. IGF-1 production is stimulated by growth hormone (GH). IGF-I binds the insulin-like growth factor 1 receptor (IGF1R) and the insulin receptor to stimulate systemic body growth. IGF-I is one of the most potent activators of the AKT signaling pathway, which stimulates cell proliferation and inhibits programmed cell death. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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