PDF DatasheetRat IGF1 / IGF-I Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant IGF1 / IGF-I based upon sequence from: Rat
Host: QP8580 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Rattus norvegicus (Rat) IGF1 / IGF-I, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8580.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Gly49 – Ala1
Amino Acid Sequence: GPETLCGAEL VDALQFVCGP RGFYFNKPTG YGSSIRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPTKSA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Rat IGF1 / IGF-I Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Rat IGF1 / IGF-I Protein General Information | |
|---|---|
| Alternate Names | |
| IGF1; IGF-I; Igf-1; Igf-I; C730016P09Rik | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IGF1 |
| Entrez Gene ID | 24482 |
| Ensemble Gene ID | ENSRNOG00000004517 |
| RefSeq Protein Accession(s) | NP_001075946.2 |
| RefSeq mRNA Accession(s) | NM_001082477.2, NM_001082478.1, NM_001082479.1, XM_006241191.2, XM_006241192.1, XM_006241193.3 |
| UniProt ID(s) | P08025 |
| UniGene ID(s) | Rn.201887 |
| COSMIC ID Link(s) | IGF1 |
| KEGG Gene ID(s) | rno:24482 |
| General Description of Recombinant Rat IGF1 / IGF-I Protein. | |
| The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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