PDF DatasheetHuman IL-15 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IL-15 based upon sequence from: Human
Host: QP10302 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human IL-15, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10302.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.5 ng/ml, corresponding to a specific activity of > 2.0 × 106 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: NWVNVISDLK KIEDLIQSMH IDATLYTESD VHPSCKVTAM KCFLLELQVI SLESGDASIH DTVENLIILA NNSLSSNGNV TESGCKECEE LEEKNIKEFL QSFVHIVQMF INTS
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human IL-15 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human IL-15 Protein General Information | |
|---|---|
| Alternate Names | |
| IL-15; IL15; Interleukin 15; IL-15 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL15 |
| Entrez Gene ID | 3600 |
| Ensemble Gene ID | ENSG00000164136 |
| RefSeq Protein Accession(s) | NP_000576.1 |
| RefSeq mRNA Accession(s) | NM_000585.4, NM_172175.2 |
| UniProt ID(s) | P40933 |
| UniGene ID(s) | Hs.168132 |
| HGNC ID(s) | HGNC:5977 |
| COSMIC ID Link(s) | IL15 |
| KEGG Gene ID(s) | hsa:3600 |
| PharmGKB ID(s) | PA29790 |
| General Description of Recombinant Human IL-15 Protein. | |
| Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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