PDF DatasheetSheep IL6 / Interleukin-6 Protein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant IL6 / Interleukin-6 Protein based upon sequence from Sheep
Host: QP6225 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Ovis aries (Sheep) IL6 / Interleukin-6 Protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6225.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Gly30 – Lys208
Amino Acid Sequence: GPLGEDFKND TTPSRLLLTT PEKTEALIKH IVDKISAIRK EICEKNDECE NSKETLAENK LKLPKMEEKD GCFQSGFNQA ICLIKTTAGL LEYQIYLDFL QNEFEGNQET VMELQSSIRT LIQILKEKIA GLITTPATHT DMLEKMQSSN EWVKNAKVII ILRSLENFLQ FSLRAIRMK
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Sheep IL6 / Interleukin-6 Protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Sheep IL6 / Interleukin-6 Protein Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL6 |
| Entrez Gene ID | 443406 |
| RefSeq Protein Accession(s) | NP_001009392.1 |
| RefSeq mRNA Accession(s) | NM_001009392.1 |
| UniProt ID(s) | P29455 |
| UniGene ID(s) | Oar.460 |
| COSMIC ID Link(s) | IL6 |
| KEGG Gene ID(s) | oas:443406 |
| General Description of Recombinant Sheep IL6 / Interleukin-6 Protein Protein. | |
| Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hatopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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