PDF DatasheetHuman IL6 / Interleukin-6 Protein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant IL6 / Interleukin-6 Protein based upon sequence from: Human
Host: QP8558 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) IL6 / Interleukin-6 Protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8558.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Val30 – Met212
Amino Acid Sequence: VPPGEDSKDV AAPHRQPLTS SERIDKQIRY ILDGISALRK ETCNKSNMCE SSKEALAENN LNLPKMAEKD GCFQSGFNEE TCLVKIITGL LEFEVYLEYL QNRFESSEEQ ARAVQMSTKV LIQFLQKKAK NLDAITTPDP TTNASLLTKL QAQNQWLQDM TTHLILRSFK EFLQSSLRAL RQM
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human IL6 / Interleukin-6 Protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human IL6 / Interleukin-6 Protein Protein General Information | |
|---|---|
| Alternate Names | |
| IL6; Interleukin-6 Protein; BSF2; IL-6; HSF; BSF-2; CDF; HGF; IFN-beta-2; IFNB2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL6 |
| Entrez Gene ID | 3569 |
| Ensemble Gene ID | ENSG00000136244 |
| RefSeq Protein Accession(s) | NP_000591.1 |
| RefSeq mRNA Accession(s) | NM_000600.4, XM_011515390.2 |
| UniProt ID(s) | P05231 |
| UniGene ID(s) | Hs.654458 |
| HGNC ID(s) | HGNC:6018 |
| COSMIC ID Link(s) | IL6 |
| KEGG Gene ID(s) | hsa:3569 |
| PharmGKB ID(s) | PA198 |
| General Description of Recombinant Human IL6 / Interleukin-6 Protein Protein. | |
| Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hatopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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