PDF DatasheetMacaque MAPT / Tau Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant MAPT / Tau based upon sequence from Macaque
Host: QP6344 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Macaca mulatta (Rhesus macaque) MAPT / Tau, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6344.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 – Leu459
Amino Acid Sequence: AEPRQEFDVM EDHAGTYGLG DRKDQEGYTM LQDQEGDTDA GLKESPLQTP AEDGSEELGS ETSDAKSTPT AEDVTAPLVD ERAPGEQAAA QPHMEIPEGT TAEEAGIGDT PSLEDEAAGH VTQARMVSKS KDGTGSDDKK AKGADGKTKI ATPRGAAPPG QKGQANATRI PAKTPPAPKT PPSSATKQVQ RKPPPAEPTS ERGEPPKSGD RSGYSSPGSP GTPGSRSRTP SLPTPPAREP KKVAVVRTPP KSPSSAKSRL QTAPVPMPDL KNVKSKIGST ENLKHQPGGG KVQIINKKLD LSNVQSKCGS KDNIKHVPGG GSVQIVYKPV DLSKVTSKCG SLGNIHHKPG GGQVEVKSEK LDFKDRVQSK IGSLDNITHV PGGGNKKIET HKLTFRENAK AKTDHGAEIV YKSPVVSGDT SPRHLSNVSS TGSIDMVDSP QLATLADEVS ASLAKQGL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Macaque MAPT / Tau Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Macaque MAPT / Tau Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Mapt |
| Entrez Gene ID | 574327 |
| Ensemble Gene ID | ENSMMUG00000004122 |
| RefSeq Protein Accession(s) | XP_014975440.1 |
| RefSeq mRNA Accession(s) | XM_015119954.1, XM_015119957.1 |
| UniProt ID(s) | P57786 |
| UniGene ID(s) | Mmu.3731 |
| COSMIC ID Link(s) | Mapt |
| KEGG Gene ID(s) | mcc:574327 |
| General Description of Recombinant Macaque MAPT / Tau Protein. | |
| Promotes microtubule assbly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma mbrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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