PDF DatasheetMouse MAPT / Tau Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant MAPT / Tau based upon sequence from: Mouse
Host: QP9264 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) MAPT / Tau, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9264.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 – Leu733
Amino Acid Sequence: ADPRQEFDTM EDHAGDYTLL QDQEGDMDHG LKESPPQPPA DDGAEEPGSE TSDAKSTPTA EDVTAPLVDE RAPDKQAAAQ PHTEIPEGIT AEEAGIGDTP NQEDQAAGHV TQGRREGQAP DLGTSDWTRQ QVSSMSGAPL LPQGLREATC QPSGTRPEDI EKSHPASELL RRGPPQKEGW GQDRLGSEEE VDEDLTVDES SQDSPPSQAS LTPGRAAPQA GSGSVCGETA SVPGLPTEGS VPLPADFFSK VSAETQASQP EGPGTGPMEE GHEAAPEFTF HVEIKASTPK EQDLEGATVV GVPGEEQKAQ TQGPSVGKGT KEASLQEPPG KQPAAGLPGR PVSRVPQLKA RVASKDRTGN DEKKAKTSTP SCAKAPSHRP CLSPTRPTLG SSDPLIKPSS PAVSPEPATS PKHVSSVTPR NGSPGTKQMK LKGADGKTGA KIATPRGAAS PAQKGTSNAT RIPAKTTPSP KTPPGSGEPP KSGERSGYSS PGSPGTPGSR SRTPSLPTPP TREPKKVAVV RTPPKSPSAS KSRLQTAPVP MPDLKNVRSK IGSTENLKHQ PGGGKVQIIN KKLDLSNVQS KCGSKDNIKH VPGGGSVQIV YKPVDLSKVT SKCGSLGNIH HKPGGGQVEV KSEKLDFKDR VQSKIGSLDN ITHVPGGGNK KIETHKLTFR ENAKAKTDHG AEIVYKSPVV SGDTSPRHLS NVSSTGSIDM VDSPQLATLA DEVSASLAKQ GL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse MAPT / Tau Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse MAPT / Tau Protein General Information | |
|---|---|
| Alternate Names | |
| MAPT; Tau; PPND; MTBT1; PPP1R103; TAU; FTDP-17; MSTD; MAPTL; MTBT2; DDPAC | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Mapt |
| Entrez Gene ID | 17762 |
| Ensemble Gene ID | ENSMUSG00000018411 |
| RefSeq Protein Accession(s) | NP_001033698.1 |
| RefSeq mRNA Accession(s) | NM_001038609.2, NM_001285454.1, NM_001285455.1, NM_001285456.1, NM_010838.4 |
| UniProt ID(s) | P10637 |
| UniGene ID(s) | Mm.1287 |
| COSMIC ID Link(s) | Mapt |
| KEGG Gene ID(s) | mmu:17762 |
| General Description of Recombinant Mouse MAPT / Tau Protein. | |
| Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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