PDF DatasheetHuman CD54 / ICAM-1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CD54 / ICAM-1 based upon sequence from: Human
Host: QP8565 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CD54 / ICAM-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8565.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Gln28 – Glu480
Amino Acid Sequence: QTSVSPSKVI LPRGGSVLVT CSTSCDQPKL LGIETPLPKK ELLLPGNNRK VYELSNVQED SQPMCYSNCP DGQSTAKTFL TVYWTPERVE LAPLPSWQPV GKNLTLRCQV EGGAPRANLT VVLLRGEKEL KREPAVGEPA EVTTTVLVRR DHHGANFSCR TELDLRPQGL ELFENTSAPY QLQTFVLPAT PPQLVSPRVL EVDTQGTVVC SLDGLFPVSE AQVHLALGDQ RLNPTVTYGN DSFSAKASVS VTAEDEGTQR LTCAVILGNQ SQETLQTVTI YSFPAPNVIL TKPEVSEGTE VTVKCEAHPR AKVTLNGVPA QPLGPRAQLL LKATPEDNGR SFSCSATLEV AGQLIHKNQT RELRVLYGPR LDERDCPGNW TWPENSQQTP MCQAWGNPLP ELKCLKDGTF PLPIGESVTV TRDLEGTYLC RARSTQGEVT RKVTVNVLSP RYE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human CD54 / ICAM-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CD54 / ICAM-1 Protein General Information | |
|---|---|
| Alternate Names | |
| CD54; ICAM-1; CD54; Icam-1; MALA-2; Ly-47 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ICAM1 |
| Entrez Gene ID | 3383 |
| Ensemble Gene ID | ENSG00000090339 |
| RefSeq Protein Accession(s) | NP_000192.2 |
| RefSeq mRNA Accession(s) | NM_000201.2 |
| UniProt ID(s) | P05362 |
| UniGene ID(s) | Hs.643447 |
| HGNC ID(s) | HGNC:5344 |
| COSMIC ID Link(s) | ICAM1 |
| KEGG Gene ID(s) | hsa:3383 |
| PharmGKB ID(s) | PA29592 |
| General Description of Recombinant Human CD54 / ICAM-1 Protein. | |
| ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagent promotes the assbly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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