Human Anti-Alpha-1-Antitrypsin Antibody Product Attributes
Tested Applications: Immunohistochemistry (IHC).
Anti-Alpha-1-Antitrypsin Antibody Clone: AAT/1378
Clone AAT/1378 Host and Isotype: Mouse IgG1
Anti-Human Alpha-1-Antitrypsin Positive Control Sample: HepG2 Cells. Tonsil, Hepatocellular Carcinoma or Histiocytoma.
Cellular Localization of Antibody
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant human Alpha-1-Antitrypsin (AAT) protein fragment
Storage Conditions: Store at 2 to 8Â° C (refrigerate). Stable for 24 months when properly stored.
Alpha-1-Antitrypsin Previously Observed Antibody Staining Patterns
Observed Subcellular, Organelle Specific Staining Data:Anti-serpina1 antibody staining is expected to be primarily localized to the vesicles.
Observed Antibody Staining Data By Tissue Type:Variations in Alpha-1-Antitrypsin antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. Low, but measureable presence of Alpha-1-Antitrypsin could be seen inglandular cells in the cervix, uterine, hepatocytes in liver, trophoblastic cells in the placenta, glandular cells in the seminal vesicle, smooth muscle cells in the smooth muscle, adipocytes in mesenchymal tissue, cells in the seminiferous ducts in testis and squamous epithelial cells in the tonsil. We were unable to detect Alpha-1-Antitrypsin in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.
Limitations and Warranty
enQuire Bio's Alpha-1-Antitrypsin Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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