Formalin-fixed, paraffin-embedded human Hodgkin's Lymphoma stained with CD15 Recombinant Rabbit Monoclonal Antibody (FUT4/1478R).

Anti-CD15 / FUT4 Antibody Clone FUT4/1478R

Name: Anti-CD15 / FUT4 Antibody Clone FUT4/1478R
Brand: enQuire Bio
Price: 199 USD
Availability: InStock

$ 199.00 – $ 549.00

Please Select Product Options Below To View The Catalog Number.

SKU: 2526-RBM8
Species: Human, Mouse, and Rat
Tested Applications: Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Rabbit IgG kappa
Mass Spec Validated?: Not MS Validated

Product Number	Description	Price
2526-RBM8-P0	Size: 20 ug, Tag: Unconjugated	$ 199.00
2526-RBM8-P1	Size: 100 ug, Tag: Unconjugated	$ 429.00
2526-RBM8-P2	Size: 200 ug, Tag: Unconjugated	$ 549.00

Shipping Information

In Stock.

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: 2526-RBM8-P0

CD15 / FUT4 General Information
Alternate Names
FUT4, Fucosyltransferase 4, Myeloid-Specific alpha (1,3) Fucosyltransferase
Molecular Weight
~220kDa
Chromosomal Location
11q21
Curated Database and Bioinformatic Data
Gene Symbol	FUT4
Entrez Gene ID	2526
Ensemble Gene ID	ENSG00000196371
RefSeq Protein Accession(s)	NP_002024
RefSeq mRNA Accession(s)	NM_002033
RefSeq Genomic Accession(s)	NC_000011, NC_018922
UniProt ID(s)	P22083
UniGene ID(s)	P22083
HGNC ID(s)	4015
Cosmic ID(s)	FUT4
KEGG Gene ID(s)	hsa:2526
PharmGKB ID(s)	PA28431
General Description of CD15 / FUT4.
CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.

Human, Mouse, and Rat Anti-CD15 / FUT4 Antibody Product Attributes

Species: Human, Mouse, and Rat

Tested Applications: Immunohistochemistry (IHC).

Clonality: Recombinant Monoclonal

Anti-CD15 / FUT4 Antibody Clone: FUT4/1478R

Clone FUT4/1478R Host and Isotype: Rabbit IgG kappa

Anti-Human, Mouse, and Rat CD15 / FUT4 Positive Control Sample: U937 cells, Reed-Sternberg's cells in Hodgkin's lymphoma

Cellular Localization of Antibody Cell surface and granular paranuclear

Buffer and Stabilizer: 10mM PBS with or without 0.05% BSA & 0.05% azide.

Antibody Concentration: 200ug/ml

Antibody Purification Method:Protein A/G Purified

Immunogen: Purified human neutrophils

Storage Conditions: Store at 2 to 8Â° C (refrigerate). Stable for 24 months when properly stored.

CD15 / FUT4 Previously Observed Antibody Staining Patterns

Observed Subcellular, Organelle Specific Staining Data:

Anti-FUT4 antibody staining is expected to be primarily localized to the vesicles.

Observed Antibody Staining Data By Tissue Type:

Variations in CD15 / FUT4 antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. An intense signal was observed in hematopoietic cells in the bone marrow. More moderate antibody staining intensity was present in hematopoietic cells in the bone marrow. Low, but measureable presence of CD15 / FUT4 could be seen in cells in the red pulp in spleen, glandular cells in the stomach and non-germinal center cells in the lymph node and tonsil. We were unable to detect CD15 / FUT4 in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.

Limitations and Warranty

enQuire Bio's CD15 / FUT4 Recombinant Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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