PDF DatasheetHuman CCL3 / Mip1a Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL3 / Mip1a based upon sequence from: Human
Host: QP5274 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5274.
Bioactivity Data: Human CCL3 / Mip1a induces THP-1 chemotaxis.
Activity was further confirmed by measuring Human PBMC chemotaxis
Activity was further confirmed by measuring Human PBMC chemotaxis
Monomer or Dimer: Monomer
Amino Acid Sequence: ASLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPGV IFLTKRSRQV CADPSEEWVQ KYVSDLELSA
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human CCL3 / Mip1a Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human CCL3 / Mip1a Protein General Information | |
|---|---|
| Alternate Names | |
| CCL3, Mip1a, G0S19-1, MIP-1alpha, LD78alpha, AI323804, Scya3, MIP1-(a), MIP1-alpha, Mip1a | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL3 |
| Entrez Gene ID | 6348 |
| Ensemble Gene ID | ENSG00000278567 |
| RefSeq Protein Accession(s) | NP_002974.1 |
| RefSeq mRNA Accession(s) | NM_002983.2 |
| UniProt ID(s) | P10147 |
| UniGene ID(s) | Hs.514107 |
| HGNC ID(s) | HGNC:10627 |
| KEGG Gene ID(s) | hsa:6348 |
| PharmGKB ID(s) | PA35559 |
| General Description of Recombinant Human CCL3 / Mip1a Protein . | |
| Macrophage inflammatory protein-1 alpha (MIP-1-alpha), also known as CCL3, is a cytokine produced by macrophages. MIP-1-alpha binds the chemokine receptors CCR1, CCR4 and CCR5 to induce inflammatory responses, including the recruitment of granulocytes and neutrophil superoxide production. The MIP-1-alpha and MIP-1-beta heterodimer exhibits antiviral activity against the human immunodeficiency virus 1 (HIV-1). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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