PDF DatasheetHuman CCL3 / Mip1a Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL3 / Mip1a based upon sequence from: Human
Host: QP10226 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human CCL3 / Mip1a, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10226.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 1.0-10 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: ASLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPGV IFLTKRSRQV CADPSEEWVQ KYVSDLELSA
Purity: Greater than 96% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human CCL3 / Mip1a Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CCL3 / Mip1a Protein General Information | |
|---|---|
| Alternate Names | |
| CCL3; Mip1a; G0S19-1; MIP-1alpha; LD78alpha; AI323804; Scya3; MIP1-(a); MIP1-alpha; Mip1a | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL3 |
| Entrez Gene ID | 6348 |
| Ensemble Gene ID | ENSG00000278567 |
| RefSeq Protein Accession(s) | NP_002974.1 |
| RefSeq mRNA Accession(s) | NM_002983.2 |
| UniProt ID(s) | P10147 |
| UniGene ID(s) | Hs.514107 |
| HGNC ID(s) | HGNC:10627 |
| KEGG Gene ID(s) | hsa:6348 |
| PharmGKB ID(s) | PA35559 |
| General Description of Recombinant Human CCL3 / Mip1a Protein. | |
| Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.