PDF DatasheetMouse CCL3 / Mip1a Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL3 / Mip1a based upon sequence from Mouse
Host: QP1450 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP1450.
Bioactivity Data: Mouse CCL3 / Mip1a induces Human PBMC chemotaxisTHP-1 chemotaxis significantly induced by less than 100 ng/ml, or activity of at least NA
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Monomer or Dimer: Monomer
Amino Acid Sequence: APYGADTPTA CCFSYSRKIP RQFIVDYFET SSLCSQPGVI FLTKRNRQIC ADSKETWVQE YITDLELNA
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Mouse CCL3 / Mip1a Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Mouse CCL3 / Mip1a Protein General Information | |
|---|---|
| Alternate Names | |
| CCL3, Mip1a, G0S19-1, MIP-1alpha, LD78alpha, AI323804, Scya3, MIP1-(a), MIP1-alpha, Mip1a | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL3 |
| Entrez Gene ID | 20302 |
| RefSeq Protein Accession(s) | NP_035467.1 |
| RefSeq mRNA Accession(s) | NM_011337.2 |
| UniProt ID(s) | Q5QNW0 |
| UniGene ID(s) | Mm.1282 |
| KEGG Gene ID(s) | mmu:20302 |
| General Description of Recombinant Mouse CCL3 / Mip1a Protein . | |
| Macrophage inflammatory protein-1 alpha (MIP-1-alpha), also known as CCL3, is a cytokine produced by macrophages. MIP-1-alpha binds the chemokine receptors CCR1, CCR4 and CCR5 to induce inflammatory responses, including the recruitment of granulocytes and neutrophil superoxide production. The MIP-1-alpha and MIP-1-beta heterodimer exhibits antiviral activity against the human immunodeficiency virus 1 (HIV-1). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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