PDF DatasheetRat CCL3 / Mip1a Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL3 / Mip1a based upon sequence from: Rat
Host: QP10292 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Rat CCL3 / Mip1a, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10292.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemoattract bioassay using human blood monocytes is in a concentration range of 10-100 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: APYGADTPTA CCFSYGRQIP RKFIADYFET SSLCSQPGVI FLTKRNRQIC ADPKETWVQE YITELELNA
Purity: Greater than 98% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Rat CCL3 / Mip1a Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Rat CCL3 / Mip1a Protein General Information | |
|---|---|
| Alternate Names | |
| CCL3; Mip1a; G0S19-1; MIP-1alpha; LD78alpha; AI323804; Scya3; MIP1-(a); MIP1-alpha; Mip1a | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL3 |
| Entrez Gene ID | 25542 |
| Ensemble Gene ID | ENSRNOG00000011205 |
| RefSeq Protein Accession(s) | NP_037157.2 |
| RefSeq mRNA Accession(s) | NM_013025.2 |
| UniProt ID(s) | P50229 |
| UniGene ID(s) | Rn.10139 |
| KEGG Gene ID(s) | rno:25542 |
| General Description of Recombinant Rat CCL3 / Mip1a Protein. | |
| Monokine with inflammatory and chemokinetic properties. Has chemotactic activity for monocytes, neutrophils, eosinophils, basophils, and lymphocytes. Required for lung TNF-alpha production, neutrophil recruitment and subsequent lung injury and may function as an autocrine mediator for the macrophage production of TNF-alpha which in turn up-regulates vascular adhesion molecules required for neutrophil influx. This protein binds heparin. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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