PDF DatasheetHuman Leptin Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Leptin based upon sequence from: Human
Host: QP5350 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5350.
Bioactivity Data: Bioactivity of Human Leptin was examined and confirmed in a Ba/F3 cell proliferation assay. This product has not been tested for in vivo use
Monomer or Dimer: Monomer
Amino Acid Sequence: MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSSKQKVTGL DFIPGLHPIL TLSKMDQTLA VYQQILTSMP SRNVIQISND LENLRDLLHV LAFSKSCHLP WASGLETLDS LGGVLEASGY STEVVALSRL QGSLQDMLWQ LDLSPGC
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Leptin Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human Leptin Protein General Information | |
|---|---|
| Alternate Names | |
| Leptin Protein, LEPD, OB, OBS | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | LEP |
| UniProt ID(s) | Q6NT58 |
| UniGene ID(s) | Hs.194236 |
| COSMIC ID Link(s) | LEP |
| General Description of Recombinant Human Leptin Protein . | |
| Leptin is a hormone that is produced by adipose tissue and plays critical roles in the physiologic regulation of body weight. Leptin acts through the leptin receptor (LEPR) to regulate adipose mass by inhibiting hunger and balancing energy usage. Leptin mutations cause severe hereditary obesity and hypogonadism in rodents and humans. Leptin also has thermogenic actions, regulates enzymes of fatty acid oxidation, and is involved in hematopoiesis, angiogenesis, wound healing, inflammation, and immune responses. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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