PDF DatasheetHuman TGF-beta 1 / TGFB1 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant TGF-beta 1 / TGFB1 based upon sequence from: Human
Host: QP773 protein expressed in CHO cells.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP773.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 500 pg/mL in the Inhibition of IL-4-induced HT-2 cell proliferation assay. The bioactivity acceptance criteria is set at 2 x 10^6 units/mg.
Monomer or Dimer: Dimer
Amino Acid Sequence: ALDTNYCFSS TEKNCCVRQL YIDFRKDLGW KWIHEPKGYH ANFCLGPCPY IWSLDTQYSK VLALYNQHNP GASAAPCCVP QALEPLPIVY YVGRKPKVEQ LSNMIVRSCK CS
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human TGF-beta 1 / TGFB1 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 0.1 % trifluoroacetic acid (TFA) and Trehalose in a 20:1 Trehalose to protein ratio
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human TGF-beta 1 / TGFB1 Protein General Information | |
|---|---|
| Alternate Names | |
| TGF-beta 1, TGFB1, TGF-beta1, Tgfb, Tgfb-1, TGFbeta1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TGFB1 |
| Entrez Gene ID | 7040 |
| Ensemble Gene ID | ENSG00000105329 |
| RefSeq Protein Accession(s) | NP_000651.3 |
| RefSeq mRNA Accession(s) | NM_000660.6 |
| UniProt ID(s) | P01137 |
| UniGene ID(s) | Hs.645227 |
| HGNC ID(s) | HGNC:11766 |
| COSMIC ID Link(s) | TGFB1 |
| KEGG Gene ID(s) | hsa:7040 |
| PharmGKB ID(s) | PA350 |
| General Description of Recombinant Human TGF-beta 1 / TGFB1 Protein. | |
| Transforming growth factor-beta 1 (TGF-b1) is a member of the TGF-beta superfamily of cytokines. Members of this family exhibit regulatory activity in immunity, proliferation, adhesion, migration, and growth inhibition pathways. TGF-b1 signals through SMAD proteins via the TGF-bRI and TGF-bRII receptors. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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