Formalin-fixed, paraffin-embedded human Tonsil stained with CD2 Monoclonal Antibody (L26 + IGEL/773)

Anti-CD20 / MS4A1 Antibody Clone L26 + IGEL/773

$ 329.00
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SKU: 931-MSM4
Species: Human, Baboon, Monkey, Cow (-), Canine (-), Pig (-), and Rat (-)
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
931-MSM4-CS1 Size: 0.5 ml, Tag: Unconjugated
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SKU: 931-MSM4-CS1
CD20 / MS4A1 General Information
Alternate Names
B-lymphocyte antigen CD20, CD20, Cluster of Differentiation 20
Molecular Weight
33-37kDa
Chromosomal Location
11q12.2
Curated Database and Bioinformatic Data
Gene SymbolMS4A1
Entrez Gene ID931
Ensemble Gene IDENSG00000156738
RefSeq Protein Accession(s)NP_068769, NP_690605
RefSeq mRNA Accession(s)NM_152866, NM_021950
RefSeq Genomic Accession(s)NG_023388, NC_018922, NC_000011
UniProt ID(s)P11836, A0A024R507
UniGene ID(s)P11836, A0A024R507
HGNC ID(s)7315
Cosmic ID(s)MS4A1
KEGG Gene ID(s)hsa:931
PharmGKB ID(s)PA31111
General Description of CD20 / MS4A1.
Recognizes a protein of 30-33kDa, which is identified as CD20. Its epitope is located in the cytoplasmic domain of CD20, was, therefore, ascribed as CD20cy in the 5th Workshop. CD20 is a non-Ig differentiation antigen of B-cells, its expression is restricted to normal, neoplastic B-cells, being absent from all other leukocytes, tissues. CD20 is expressed by pre B-cells, persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This MAb can be used for immunophenotyping of leukemia, malignant cells, B lymphocyte detection in peripheral blood, B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood, lymphoid tissues, their derived lymphomas. In lymphoid tissue, germinal center blasts, B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkins disease, particularly of lymphocyte predominant type.

Human, Baboon, Monkey, Cow (-), Canine (-), Pig (-), and Rat (-) Anti-CD20 / MS4A1 Antibody Product Attributes

Species: Human, Baboon, Monkey, Cow (-), Canine (-), Pig (-), and Rat (-)
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC).
Clonality: Monoclonal
Anti-CD20 / MS4A1 Antibody Clone: L26 + IGEL/773
Clone L26 + IGEL/773 Host and Isotype: Mouse IgG
Anti-Human, Baboon, Monkey, Cow (-), Canine (-), Pig (-), and Rat (-) CD20 / MS4A1 Positive Control Sample: Daudi, Raji,, U266,, human lymphocytes. Lymph nodes, tonsils.
Cellular Localization of Antibody Predominantly cell surface with some cytoplasmic
Buffer and Stabilizer: Tissue culture supernatant with 0.05% Azide.
Antibody Concentration: Not applicable
Antibody Purification Method:Culture Supernatant
Immunogen: Human tonsil B cells (L26); Recombinant human MS4A1 protein (IGEL/773)
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

CD20 / MS4A1 Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's CD20 / MS4A1 Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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Anti-CD20 / MS4A1 Antibody Clone L26 + IGEL/773