Recombinant Mouse TNF-alpha Protein

$ 98.00$ 1,838.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10470
Species: Mouse
Available Tags: Untagged
Host: E. coli
Purity: Greater than 98% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 157

Product NumberDescriptionPrice
QP10470-ec-5ug Size: 5 ug, Tag: Untagged (Native Protein) $ 98.00
QP10470-ec-20ug Size: 20 ug, Tag: Untagged (Native Protein) $ 248.00
QP10470-ec-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 1,018.00
QP10470-ec-250ug Size: 250 ug, Tag: Untagged (Native Protein) $ 1,838.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP10470-ec-5ug
Recombinant Mouse TNF-alpha Protein General Information
Alternate Names
TNF-alpha; Tnfa; Tnfsf1a; Tnlg1f; TNF-a; DIF; TNF-alpha; TNFalpha; TNFSF2
Curated Database and Bioinformatic Data
Gene SymbolTNF
Entrez Gene ID21926
Ensemble Gene IDENSMUSG00000024401
RefSeq Protein Accession(s)NP_001265530.1
RefSeq mRNA Accession(s)NM_001278601.1, NM_013693.3
UniProt ID(s)P06804
UniGene ID(s)Mm.1293
COSMIC ID Link(s)TNF
KEGG Gene ID(s)mmu:21926
General Description of Recombinant Mouse TNF-alpha Protein.
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.; The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.

Mouse TNF-alpha Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant TNF-alpha based upon sequence from: Mouse
Host: QP10470 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Mouse TNF-alpha, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10470.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cytotoxicity assay using murine L929 cells is less than 0.1 ng/ml, corresponding to a specific activity of > 1.0 × 107 IU/mg in the presence of actinomycin D.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: MLRSSSQNSS DKPVAHVVAN HQVEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLVY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VNLLSAVKSP CPKDTPEGAE LKPWYEPIYL GGVFQLEKGD QLSAEVNLPK YLDFAESGQV YFGVIAL
Purity: Greater than 98% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Mouse TNF-alpha Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.2, lyophilized
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Mouse TNF-alpha Protein

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