PDF DatasheetMacaque CD40L / CD154 / TNFSF5 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CD40L / CD154 / TNFSF5 based upon sequence from Macaque
Host: QP5786 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Macaca mulatta (Rhesus macaque) CD40L / CD154 / TNFSF5, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5786.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Val44 – Leu261
Amino Acid Sequence: VYLHRRLDKI EDERNLHEDF VFMKTIQRCN TGERSLSLLN CEEIKSQFEG FVKDIMLNKE EKKKENSFEM QKGDQNPQIA AHVISEASSK TTSVLQWAEK GYYTMSNNLV TLENGKQLTV KRQGLYYIYA QVTFCSNREA SSQAPFIASL CLKSPGRFER ILLRAANTHS SAKPCGQQSI HLGGVFELQP GASVFVNVTD PSQVSHGTGF TSFGLLKL
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Macaque CD40L / CD154 / TNFSF5 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Macaque CD40L / CD154 / TNFSF5 Protein General Information | |
|---|---|
| Alternate Names | |
| CD40L, CD154, TNFSF5, CD154, IGM, Ly-62, TRAP, Tnlg8b, HIGM1, CD40-L, Cd40l, Ly62, T-BAM, IMD3, Tnfsf5, gp39 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CD40LG |
| Entrez Gene ID | 574160 |
| RefSeq Protein Accession(s) | NP_001028011.1 |
| RefSeq mRNA Accession(s) | NM_001032839.1 |
| UniProt ID(s) | P63304 |
| UniGene ID(s) | Mmu.3581 |
| COSMIC ID Link(s) | CD40LG |
| KEGG Gene ID(s) | mcc:574160 |
| General Description of Recombinant Macaque CD40L / CD154 / TNFSF5 Protein. | |
| Cytokine that binds to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.