Formalin paraffin Rat Stomach stained with Cytokeratin, HMW Monoclonal Antibody (KRTH/176).
Formalin paraffin Rat Stomach stained with Cytokeratin, HMW Monoclonal Antibody (KRTH/176).Formalin paraffin Rat Oviduct with Cytokeratin, HMW Monoclonal Antibody (KRTH/176).

Anti-Cytokeratin Antibody Clone KRTH/1076

$ 488.00
Please Select Product Options Below To View The Catalog Number.

SKU: MSM9-1076
Species: Human, Rat, and Broad Species Reactivity
Tested Applications: ELISA Flow Cytometry, Immunofluorescence, Western Blot, Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1 kappa
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
MSM9-1076-P1 Size: 100 ug, Tag: Unconjugated
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In Stock.
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
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Bioactivity (test results eg. IU/ml):

SKU: MSM9-1076-P1
Cytokeratin General Information
Alternate Names
KRT2B, KRT2P, HUMCYT2A, Keratin, Type II Cytoskeletal 2 Oral, K2P, K76, CK-2P, Keratin 2p, Keratin-76, Cytokeratin 2, Cytokeratin-2P, Type-II Keratin Kb9, anti-KRT2B antibody, anti-KRT2P antibody, anti-HUMCYT2A antibody, anti-Keratin antibody, anti-Type II Cytoskeletal 2 Oral antibody, anti-K2P antibody, anti-K76 antibody, anti-CK-2P antibody, anti-Keratin 2p antibody, anti-Keratin-76 antibody, anti-Cytokeratin 2 antibody, anti-Cytokeratin-2P antibody, anti-Type-II Keratin Kb9 antibody
Molecular Weight
67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8)
Chromosomal Location
Curated Database and Bioinformatic Data
Gene SymbolKRT76
Entrez Gene ID51350
Ensemble Gene IDENSG00000185069
RefSeq Protein Accession(s)NP_056932
RefSeq mRNA Accession(s)NM_015848,
RefSeq Genomic Accession(s)NG_012420, NC_000012, NC_018923
UniProt ID(s)Q01546
UniGene ID(s)Q01546
HGNC ID(s)24430
Cosmic ID(s)KRT76
KEGG Gene ID(s)hsa:51350
PharmGKB ID(s)PA147357785
General Description of Cytokeratin.
This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50 , 48, 46, 45,, 40kDa. Many studies have shown the usefulness of keratins as markers in cancer research, tumor diagnosis.

Human, Rat, and Broad Species Reactivity Anti-Cytokeratin Antibody Product Attributes

Species: Human, Rat, and Broad Species Reactivity
Tested Applications: ELISA Flow Cytometry, Immunofluorescence, Western Blot, Immunohistochemistry (IHC).
Application Notes: ELISA Flow Cytometry (0.5-1ug of antibody/million cells in 0.1ml), Immunofluorescence (1-2ug of antibody/ml), Western Blot (0.5-1ug of antibody/ml f), Immunohistochemistry (IHC) (Formalin-fixed) (0.25-0.5ug of antibody/ml for 30 min at RT)
Clonality: Monoclonal
Anti-Cytokeratin Antibody Clone: KRTH/1076
Clone KRTH/1076 Host and Isotype: Mouse IgG1 kappa
Anti-Human, Rat, and Broad Species Reactivity Cytokeratin Positive Control Sample: Skin, Adenocarcinomas
Cellular Localization of Antibody Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant human KRT76 protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

Cytokeratin Previously Observed Antibody Staining Patterns

Observed Antibody Staining Data By Tissue Type:

Variations in Cytokeratin antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. Low, but measureable presence of Cytokeratin could be seen in. We were unable to detect Cytokeratin in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.

Observed Antibody Staining Data By Tissue Disease Status:

Tissues from cancer patients, for instance, have their own distinct pattern of Cytokeratin expression as measured by anti-Cytokeratin antibody immunohistochemical staining. The average level of expression by tumor is summarized in the table below. The variability row represents patient to patient variability in IHC staining.

Sample Type breast cancer carcinoid cervical cancer colorectal cancer endometrial cancer glioma head and neck cancer liver cancer lung cancer lymphoma melanoma ovarian cancer pancreatic cancer prostate cancer renal cancer skin cancer stomach cancer testicular cancer thyroid cancer urothelial cancer
Signal Intensity + - - + + - + + - - - + + - - - - - + -
KRT76 Variability ++ ++ ++ ++ ++ + ++ ++ ++ + ++ ++ ++ ++ ++ + ++ ++ ++ ++

Limitations and Warranty

enQuire Bio's Cytokeratin, Basic Anti-Human, Rat Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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Anti-Cytokeratin Antibody Clone KRTH/1076