PDF DatasheetMacaque IL4 / Interleukin-4 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IL4 / Interleukin-4 based upon sequence from: Macaque
Host: QP10337 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Rhesus Macaque IL4 / Interleukin-4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10337.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 1.0 ng/ml, corresponding to a specific activity of > 1.0 × 106 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: HNCHIALREI IETLNSLTEQ KTLCTKLTIT DILAASKNTT EKETFCRAAT VLRQFYSHHE KDTRCLGATA QQFHRHKQLI RFLKRLDRNL WGLAGLNSCP VKEANQSTLE DFLERLKTIM REKYSKCSS
Purity: Greater than 96% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Macaque IL4 / Interleukin-4 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered 2 × PBS, pH 7.4, 5 % trehalose, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Macaque IL4 / Interleukin-4 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL4 |
| UniProt ID(s) | P51492 |
| COSMIC ID Link(s) | IL4 |
| General Description of Recombinant Macaque IL4 / Interleukin-4 Protein. | |
| Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes (By similarity). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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