PDF DatasheetHuman IL4 / Interleukin-4 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant IL4 / Interleukin-4 based upon sequence from Human
Host: QP6223 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) IL4 / Interleukin-4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6223.
Bioactivity Data: Untested
Full Length? Full Length of Mature Protein
Expression Region: His25 – Ser153
Amino Acid Sequence: HKCDITLQEI IKTLNSLTEQ KTLCTELTVT DIFAASKNTT EKETFCRAAT VLRQFYSHHE kDaTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human IL4 / Interleukin-4 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human IL4 / Interleukin-4 Protein General Information | |
|---|---|
| Alternate Names | |
| IL4, Interleukin-4, BSF-1, BSF1, IL-4, BCGF1, BCGF-1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL4 |
| Entrez Gene ID | 3565 |
| Ensemble Gene ID | ENSG00000113520 |
| RefSeq Protein Accession(s) | NP_000580.1 |
| RefSeq mRNA Accession(s) | NM_000589.3, NM_172348.2 |
| UniProt ID(s) | P05112 |
| UniGene ID(s) | Hs.73917 |
| HGNC ID(s) | HGNC:6014 |
| COSMIC ID Link(s) | IL4 |
| KEGG Gene ID(s) | hsa:3565 |
| PharmGKB ID(s) | PA197 |
| General Description of Recombinant Human IL4 / Interleukin-4 Protein. | |
| Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.