PDF DatasheetSheep IL4 / Interleukin-4 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant IL4 / Interleukin-4 based upon sequence from Sheep
Host: QP6224 protein expressed in E. coli.
Tag: His-Myc
Protein Construction: A DNA sequence encoding the Ovis aries (Sheep) IL4 / Interleukin-4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6224.
Bioactivity Data: Untested
Full Length? Full Length of Mature Protein
Expression Region: His25 – Cys135
Amino Acid Sequence: HKCDITLEEI IKTLNILTSR KNSCMELPVA DVFAAPKNAT EKETFCRAGI ELRRIYRSHM CLNKFLGGLD RNLSSLASKT CSVNEAKTST STLRDLLERL KTIMREKYSK C
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Sheep IL4 / Interleukin-4 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Sheep IL4 / Interleukin-4 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL4 |
| Entrez Gene ID | 443327 |
| RefSeq Protein Accession(s) | NP_001009313.2 |
| RefSeq mRNA Accession(s) | NM_001009313.2 |
| UniProt ID(s) | P30368 |
| UniGene ID(s) | Oar.377 |
| COSMIC ID Link(s) | IL4 |
| KEGG Gene ID(s) | oas:443327 |
| General Description of Recombinant Sheep IL4 / Interleukin-4 Protein. | |
| Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.