PDF DatasheetHuman IL4 / Interleukin-4 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant IL4 / Interleukin-4 based upon sequence from: Human
Host: QP8557 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) IL4 / Interleukin-4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8557.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: His25 – Ser153
Amino Acid Sequence: HKCDITLQEI IKTLNSLTEQ KTLCTELTVT DIFAASKNTT EKETFCRAAT VLRQFYSHHE KDTRCLGATA QQFHRHKQLI RFLKRLDRNL WGLAGLNSCP VKEANQSTLE NFLERLKTIM REKYSKCSS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human IL4 / Interleukin-4 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human IL4 / Interleukin-4 Protein General Information | |
|---|---|
| Alternate Names | |
| IL4; Interleukin-4; BSF-1; BSF1; IL-4; BCGF1; BCGF-1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL4 |
| Entrez Gene ID | 3565 |
| Ensemble Gene ID | ENSG00000113520 |
| RefSeq Protein Accession(s) | NP_000580.1 |
| RefSeq mRNA Accession(s) | NM_000589.3, NM_172348.2 |
| UniProt ID(s) | P05112 |
| UniGene ID(s) | Hs.73917 |
| HGNC ID(s) | HGNC:6014 |
| COSMIC ID Link(s) | IL4 |
| KEGG Gene ID(s) | hsa:3565 |
| PharmGKB ID(s) | PA197 |
| General Description of Recombinant Human IL4 / Interleukin-4 Protein. | |
| Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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